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Synthesis and
Characterization of New Schiff Base Derived from PVA and
Erythroascorbic Acid Derivative and Study Its Effect on the
Activity Ach Enzyme (In Vitro |
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Schiff base
derived from PVA and Erythroascorbic acid derivative
(pentulosono-ɣ-lactone-2, 3- nedianisoate) was synthesized and
characterized by Thin Layer Chromatography (TLC) and FTIR
spectra, aldehyde was also characterized by (U.V-Vis), 1HNMR,
13CNMR and mass spectra. The inhibitory effect of prepared
polymer on the activity of human serum Cholinesrerase has been
studied in vitro. The polymer showed a remarkable activity at
low concentration (4.5*10-3 – 4.5*10-8 M). |
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